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Ultrasonic Synthesis and Preliminary Evaluation of Anticoronaviral Activity of 6,7-Dimethoxy-4-(4-(4-methoxyphenyl) piperazin-1-yl)-1-methylquinolin-1-ium Iodide by Aleksey A. Vasilev Peter P. Grozdanov Ivanka Nikolova Valentin S. Lozanov & Meglena I. Kandinska

Author:Aleksey A. Vasilev, Peter P. Grozdanov, Ivanka Nikolova, Valentin S. Lozanov & Meglena I. Kandinska , Date: April 15, 2024 ,Views: 119

Ultrasonic Synthesis and Preliminary Evaluation of Anticoronaviral Activity of 6,7-Dimethoxy-4-(4-(4-methoxyphenyl) piperazin-1-yl)-1-methylquinolin-1-ium Iodide by Aleksey A. Vasilev Peter P. Grozdanov Ivanka Nikolova Valentin S. Lozanov & Meglena I. Kandinska

Author:Aleksey A. Vasilev, Peter P. Grozdanov, Ivanka Nikolova, Valentin S. Lozanov & Meglena I. Kandinska
Format: pdf
Tags: Quinoline scaffold is one of the most intensively utilized pharmacophores in drug design because of the variety of activities demonstrated by different quinoline-based therapeutics or drug-candidates. Herein, we describe an environmentally tolerant two-step procedure as a convenient synthetic approach to novel chloroquine and hydroxychloroquine analogues. The structures of the newly synthesized compounds are estimated by 1H NMR, 13C NMR, LC-MS spectrometry and IR spectroscopy., chloroquine; hydroxychloroquine; quinoline; anticoronaviral activity; ultrasonictreatment


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Ultrasonic Synthesis and Preliminary Evaluation of Anticoronaviral Activity of 6,7-Dimethoxy-4-(4-(4-methoxyphenyl) piperazin-1-yl)-1-methylquinolin-1-ium Iodide by Aleksey A. Vasilev Peter P. Grozdanov Ivanka Nikolova Valentin S. Lozanov & Meglena I. Kandinska.pdf


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